Inositol & its Phosphates: Basic Science to Practical Applications

Mineralization Disorders

Author(s): A.K.M. Shamsuddin and Guang-Yu Yang

Pp: 149-163 (15)

DOI: 10.2174/9781681080079115010014

* (Excluding Mailing and Handling)


Owing to the ability to chelate calcium, InsP6 has been studied as a preventive and therapeutic agent for abnormal calcification in various tissues such as blood vessels in atherosclerosis and skin in calcinosis cutis; kidney and salivary gland stones; prevention of dental caries and bone loss as in osteoporosis, etc. The results are very promising for wide-range practical application of InsP6 especially against the serious debilitating problem of osteoporosis amongst the seniors, globally.

Keywords: Calcinosis cutis, caries, crystallization inhibitor, dystrophic calcification, fluoride, hydroxyapatite, kidney stone, metastatic calcification, osteoblast, osteoclast, pyrophosphate, sialolithiasis, titratable acidity, tooth decay.

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