Advances in Organic Synthesis

Volume: 5

Chiral Molecular Receptors Based on Trans-Cyclohexane-1,2- Diamine

Author(s): Ignacio Alfonso

Pp: 51-100 (50)

DOI: 10.2174/9781608054800113050004

* (Excluding Mailing and Handling)


This review highlights the development of new receptors based on enantiopure trans-cyclohexane-1,2-diamine, a chiral building block presenting unique structural and conformational properties. Different architectures sharing this structural motif, which were prepared following several synthetic approaches, have been summarized from the recent literature.

Keywords: Trans-cyclohexane-1, 2-diamine, chiral receptor, nitrogen, molecular recognition, macrocycles.

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