Nanoparticles and Nanocarriers Based Pharmaceutical Formulations

Polymeric Nanoparticles as Drug Delivery System: Basic Concepts and Applications

Author(s): Sakshi Tiwari, Bina Gidwani, Priya Namdeo, Atul Tripathi, Ravindra Kumar Pandey, Shiv Shankar Shukla, Veenu Joshi, Vishal Jain, Vikas Kumar Jain and Amber Vyas *

Pp: 26-54 (29)

DOI: 10.2174/9789815049787122010004

* (Excluding Mailing and Handling)


Delivering drugs through various delivery systems into the body for successful treatment of diseases is most entrancing deeds for the pharmaceutical analyst. Conventional drug delivery systems have various hindrances like loss of medication and poor bioavailability of drugs. Polymer-based nanocarriers such as polymeric nanoparticles upgrade bioavailability of drug, delivery of drug to specific site and improve solubility of drugs. They are widely explored as controlled, precise, sustained and continuous release systems for drug delivery and are easily incorporated and appropriate for practically all parts of nanomedicines and bring new trust in field of drug conveyance by redesigning drug viability and diminishing drug toxicity. This chapter mainly focuses on polymers and techniques engaged with advancement of polymer-based nanoparticles and their applications in therapeutic intervention. 

Keywords: Bioavailability, Controlled release, Diagnosis, Dispersion, Drug delivery system, Drug efficacy, Drug toxicity, Diffusion, Polymeric nanoparticles, Macromolecules, Natural polymers, Nanoprecipitation, Interfacial polymerization, Synthetic polymers, Targeted drug delivery, Potent drug delivery, Polymerization, Sustained release, Treatment, Solvent evaporation.

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