Molecular Bases of Neurodegenerative Disorders of the Retina

Ciliary Trafficking in Vertebrate Photoreceptors

Author(s): Hemant Khanna

Pp: 1-15 (15)

DOI: 10.2174/9781681085487117010003

* (Excluding Mailing and Handling)


Cilia are microtubule-based extensions of the plasma membrane of cells. These extensions detect extrinsic cues that are crucial for carrying out a myriad of developmental and homeostatic signaling cascades. Cilia have evolved diverse means to mediate signaling cascades in a cell-type specific manner. In this article, I have summarized the conserved mechanisms of formation of cilia and their structural and functional specialization for light detection.

Keywords: Basal body, Cilia, Photoreceptor, Retina.

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